Article
The Ets transcription factor GABP is required for postsynaptic differentiation in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Aug 2000
Briguet A, Ruegg M A
Abstract excerpt
At chemical synapses, neurotransmitter receptors are concentrated in the postsynaptic membrane. During the development of the neuromuscular junction, motor neurons induce aggregation of acetylcholine receptors (AChRs) underneath the nerve terminal by the redistribution of existing AChRs and preferential transcription of the AChR subunit genes in subsynaptic myonuclei. Neural agrin, when expressed in nonsynaptic...
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