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Article

BRCT domain-containing protein PTIP is essential for progression through mitosis.

Molecular and cellular biology - 1 Mar 2003

Cho Eun Ah, Prindle Marc J, Dressler Gregory R

Abstract excerpt

The Pax transactivation domain-interacting protein (PTIP) is a large nuclear protein with multiple BRCT domains that was identified on the basis of its interaction with transcription factors of the Pax and Smad families. To address the function of PTIP during mouse development, we generated a constitutive null allele. Homozygous PTIP mutants are developmentally retarded, disorganized, and embryonic lethal by day...

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Identifiers

PMID: 12588986
DOI: 10.1128/MCB.23.5.1666-1673.2003
PMCID: PMC151700

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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