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Article

Cancer progression and tumor cell motility are associated with the FGFR4 Arg(388) allele.

Cancer research - 1 Feb 2002

Bange Johannes, Prechtl Dieter, Cheburkin Yuri, Specht Katja, Harbeck Nadia, Schmitt Manfred, Knyazeva Tatjana, Müller Susanne, Gärtner Silvia, Sures Irmi, Wang Hongyang, Imyanitov Evgeny, Häring Hans-Ulrich, Knayzev Pjotr, Iacobelli Stefano, Höfler Heinz, Ullrich Axel

Abstract excerpt

Expression analysis of genes encoding components of the phosphotyrosine signaling system by cDNA array hybridization revealed elevated levels of FGFR4 transcripts in several mammary carcinoma cell lines. In the FGFR4 gene transcript from MDA-MB-453 mammary carcinoma cells, a G to A conversion was discovered that results in the substitution of glycine by arginine at position 388 in the transmembrane domain of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11830541

Genes

FGFR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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