Article
The fibroblast growth factor receptor-4 Arg388 allele is associated with gastric cancer progression.
Annals of surgical oncology - 1 Dec 2010
Ye Yanwei, Shi Yingqiang, Zhou Ye, Du Chunyan, Wang Chunmeng, Zhan Heqin, Zheng Biqiang, Cao Xi, Sun Meng-Hong, Fu Hong
Abstract excerpt
BACKGROUND: Fibroblast growth factor receptor 4 (FGFR4) Gly388Arg polymorphism, located in the FGFR4 gene exon 9, was reported to be associated with malignant tumors prognosis; however, there has been no relevant research for gastric cancer. The purpose of this study was to investigate the clinical significance of FGFR4 Gly388Arg polymorphism as well as the mRNA expression of FGFR4 in patients with gastric...
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