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Article

FGFR4 Gly388Arg polymorphism may affect the clinical stage of patients with lung cancer by modulating the transcriptional profile of normal lung.

International journal of cancer - 15 Jun 2009

Falvella Felicia S, Frullanti Elisa, Galvan Antonella, Spinola Monica, Noci Sara, De Cecco Loris, Nosotti Mario, Santambrogio Luigi, Incarbone Matteo, Alloisio Marco, Calabrò Elisa, Pastorino Ugo, Skaug Vidar, Haugen Aage, Taioli Emanuela, Dragani Tommaso A

Abstract excerpt

The association of the fibroblast growth factor receptor 4 (FGFR4) Gly388Arg polymorphism with clinical stage and overall survival in a series of 541 Italian lung adenocarcinoma (ADCA) patients indicated a significantly decreased survival in patients carrying the rare Arg388 allele as compared to that in Gly/Gly homozygous patients [hazard ratio (HR) = 1.5; 95% confidence interval (CI) 1.1-1.9], with the decrease...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19296538
DOI: 10.1002/ijc.24302

Genes

FGFR4
FGF18
FGF19
FGF9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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FGFR4 Gly388Arg polymorphism may affect the clinical stage of patients with lung cancer by modulating the transcriptional profile of normal lung.PMID 19296538Read ↗

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