Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional effects of NAD(P)H oxidase p22(phox) C242T mutation in human leukocytes and association with thrombotic cerebral infarction.

Atherosclerosis - 1 Jul 2004

Shimo-Nakanishi Yumi, Hasebe Takeshi, Suzuki Asuka, Mochizuki Hideki, Nomiyama Takashi, Tanaka Yasushi, Nagaoka Isao, Mizuno Yoshikuni, Urabe Takao

Abstract excerpt

BACKGROUND: Previous study showed that polymorphism of the NAD(P)H oxidase p22(phox) gene is associated with atherosclerosis, although others could not confirm such association. We investigated the association between p22(phox) C242T polymorphism and thrombotic cerebral infarction and the role of this polymorphism on superoxide-production activity in human neutrophils and promyelocytic HL-60 cells as a model...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cerebral Infarction
Share to Cytochromes c

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HL-60 Cells

Share to Intracranial Thrombosis

Share to Leukocytes

Share to NADPH Dehydrogenase

Share to NADPH Oxidases

Share to Superoxides

Source

Identifiers

PMID: 15186954
DOI: 10.1016/j.atherosclerosis.2004.01.043

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional effects of NAD(P)H oxidase p22(phox) C242T mutation in human leukocytes and association with thrombotic cerebral infarction.PMID 15186954Read ↗

C242T polymorphism of NADPH oxidase p22 PHOX gene and ischemic cerebrovascular disease in the Japanese population.Semantic proximity Read ↗

Functional effect of the C242T polymorphism in the NAD(P)H oxidase p22phox gene on vascular superoxide production in atherosclerosis.Semantic proximity Read ↗

p22phox C242T Single-Nucleotide Polymorphism Inhibits Inflammatory Oxidative Damage to Endothelial Cells and Vessels.Semantic proximity Read ↗

Oxidative stress in arterial hypertension: role of NAD(P)H oxidase.Semantic proximity Read ↗

The C242T polymorphism of the p22phox component of NAD(P)H oxidase and vascular risk. Two case-control studies and a meta-analysis.Semantic proximity Read ↗

The C242T polymorphism of the NAD(P)H oxidase p22phox subunit is associated with an enhanced risk for cerebrovascular disease at a young age.Semantic proximity Read ↗

Impact of NAD(P)H oxidase p22 phox gene polymorphism on vascular aging in Korean centenarian and nonagenarian.Semantic proximity Read ↗

Oxidative stress and cardiovascular risk: the role of vascular NAD(P)H oxidase and its genetic variants.Semantic proximity Read ↗

The A640G and C242T p22(phox) polymorphisms in patients with coronary artery disease.Semantic proximity Read ↗

Association between NADPH oxidase p22(phox) C242T polymorphism and ischemic cerebrovascular disease: a meta-analysis.Semantic proximity Read ↗

Association between rs4673 (C/T) and rs13306294 (A/G) haplotypes of NAD(P)H oxidase p22phox gene and severity of stenosis in coronary arteries.Semantic proximity Read ↗

C242T CYBA polymorphism of the NADPH oxidase is associated with reduced respiratory burst in human neutrophils.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.