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Article

Oxidative stress in arterial hypertension: role of NAD(P)H oxidase.

Hypertension (Dallas, Tex. : 1979) - 1 Dec 2001

Zalba G, San José G, Moreno M U, Fortuño M A, Fortuño A, Beaumont F J, Díez J

Abstract excerpt

Increased vascular reactive oxygen species production, especially superoxide anion, contributes significantly in the functional and structural alterations present in hypertension. An enhanced superoxide production causes a diminished NO bioavailability by an oxidative reaction that inactivates NO. Exaggerated superoxide levels and a low NO bioavailability lead to endothelial dysfunction and hypertrophy of...

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Identifiers

PMID: 11751724
DOI: 10.1161/hy1201.099611

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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