Article
Oxidative stress and cardiovascular risk: the role of vascular NAD(P)H oxidase and its genetic variants.
European journal of clinical investigation - 1 May 2005
Soccio M, Toniato E, Evangelista V, Carluccio M, De Caterina R
Abstract excerpt
Several risk factors for coronary artery disease (CAD) induce atherosclerosis through endothelial activation and dysfunction, and ample evidence now suggests that the balance between production and removal of reactive oxygen species (ROS) - a condition termed oxidative stress - is implicated in such processes. A main source of ROS in vascular cells is the reduced nicotinamide adenine dinucleotide/nicotinamide...
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