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Article

The C242T polymorphism of the p22phox component of NAD(P)H oxidase and vascular risk. Two case-control studies and a meta-analysis.

Thrombosis and haemostasis - 1 Mar 2008

Di Castelnuovo Augusto, Soccio Manola, Iacoviello Licia, Evangelista Virgilio, Consoli Agostino, Vanuzzo Diego, Diviacco Silvia, Carluccio Marisa, Rignanese Lucia, De Caterina Raffaele

Abstract excerpt

NAD(P)H oxidase is a prominent source of reactive oxygen species in the vasculature. Vascular NAD(P)H oxidase is comprised of several subunits, one of which, p22phox, is encoded by a gene exhibiting several allelic variants. Here the C(242)T nucleotide transition has been found to alter superoxid...

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PMID: 18327409
DOI: 10.1160/TH07-08-0480

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CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18327409-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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