Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The A640G and C242T p22(phox) polymorphisms in patients with coronary artery disease.

Antioxidants & redox signaling - 1 Aug 2002

Zafari A Maziar, Davidoff Madalyn N, Austin Harland, Valppu Liisa, Cotsonis George, Lassègue Bernard, Griendling Kathy K

Abstract excerpt

Oxidative stress plays a significant role in the pathogenesis of coronary artery disease (CAD). A p22(phox)-based NAD(P)H oxidase acts as a potent superoxide-generating system in the vasculature. We studied the association of the A640G and the C242T polymorphisms with clinical risk factors, endothelial function, and severity of CAD in a cohort of 216 patients referred for coronary angiography. The frequency of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brachial Artery
Share to Coronary Angiography

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Artery Disease

Share to Endothelium, Vascular

Share to NADPH Dehydrogenase

Share to NADPH Oxidases

Share to Ultrasonography

Share to Vasodilator Agents

Source

Identifiers

PMID: 12230880
DOI: 10.1089/15230860260220184

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The A640G and C242T p22(phox) polymorphisms in patients with coronary artery disease.PMID 12230880Read ↗

Relationship of the C242T p22phox gene polymorphism to angiographic coronary artery disease and endothelial function.Semantic proximity Read ↗

The p22 phox A640G gene polymorphism but not the C242T gene variation is associated with coronary heart disease in younger individuals.Semantic proximity Read ↗

NADH/NADPH oxidase <i>p22</i><i>phox</i> C242T polymorphism and coronary artery disease in the Australian populationSemantic proximity Read ↗

The p22 phox polymorphism C242T is not associated with CHD risk in Asian Indians and Chinese.Semantic proximity Read ↗

C242T polymorphism of the p22 phox gene is not associated with peripheral arterial occlusive disease.Semantic proximity Read ↗

The C242T polymorphism of the p22phox component of NAD(P)H oxidase and vascular risk. Two case-control studies and a meta-analysis.Semantic proximity Read ↗

Oxidative stress and cardiovascular risk: the role of vascular NAD(P)H oxidase and its genetic variants.Semantic proximity Read ↗

A variant of p22(phox), involved in generation of reactive oxygen species in the vessel wall, is associated with progression of coronary atherosclerosis.Semantic proximity Read ↗

Polymorphism of the NADH/NADPH Oxidase <i>p22 phox</i> Gene in Patients With Coronary Artery DiseaseSemantic proximity Read ↗

Association between rs4673 (C/T) and rs13306294 (A/G) haplotypes of NAD(P)H oxidase p22phox gene and severity of stenosis in coronary arteries.Semantic proximity Read ↗

Association of nicotinamide adenine dinucleotide phosphate oxidase p22phox gene 549C>T polymorphism with coronary artery disease.Semantic proximity Read ↗

Impact of NAD(P)H oxidase p22 phox gene polymorphism on vascular aging in Korean centenarian and nonagenarian.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.