Patterns of nucleotide substitutions inferred from the phylogenies of the class I major histocompatibility complex genes.

doi:10.1007/BF00178595

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Article

Patterns of nucleotide substitutions inferred from the phylogenies of the class I major histocompatibility complex genes.

Journal of molecular evolution - 1 Sept 1992

Imanishi T, Gojobori T

Abstract excerpt

Patterns of nucleotide substitutions in human major histocompatibility complex (MHC) class I genes were estimated by using phylogenetic trees of DNA sequences. The pattern is defined as a set of 12 parameters, each of which represents the relative frequency of substitutions from a particular nucl...

Topics

Codon
Genes, MHC Class I
HLA-A Antigens
HLA-B Antigens
Humans
Molecular Sequence Data
Mutation
Phylogeny
Pseudogenes
Selection, Genetic

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