Article
The synonymous substitution rate of the major histocompatibility complex loci in primates.
Proceedings of the National Academy of Sciences of the United States of America - 15 Aug 1993
Satta Y, O'hUigin C, Takahata N, Klein J
Abstract excerpt
Because the divergence of many allelic lineages at the major histocompatibility complex (MHC) loci predates species divergence, standard methods of calculating synonymous substitution rates are not applicable to this system. We used three alternative methods of rate estimation: one based on the minimum number of substitutions (Dm), another on the nucleotide difference (Dxy), and the third on the net nucleotide...
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