Article
Overdispersed molecular clock at the major histocompatibility complex loci.
Proceedings. Biological sciences - 22 Jan 1991
Takahata N
Abstract excerpt
The extent of amino acid differences of major histocompatibility complex molecules within species is unusually high, consistent with the finding that some pairs of alleles have persisted for more than ten million years and the view that the polymorphism has been maintained by natural selection. T...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Biological Evolution
- DNA
- Humans
- Major Histocompatibility Complex
- Mice
- Models, Genetic
- Selection, Genetic
- Species Specificity
- Time Factors