Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolutionary relationships of class II major-histocompatibility-complex genes in mammals.

Molecular biology and evolution - 1 Nov 1990

Hughes A L, Nei M

Abstract excerpt

The major histocompatibility complex (MHC) class II molecule consists of noncovalently associated alpha and beta chains. In mammals studied so far, the class II MHC can be divided into a number of regions, each containing one or more alpha-chain genes (A genes) and beta-chain genes (B genes), and it has been known for some time that orthologous relationships exist between genes in corresponding regions from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acids
Share to Base Sequence
Share to Biological Evolution

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, MHC Class II

Share to Genetic Variation

Share to Molecular Sequence Data

Share to Phylogeny

Share to Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 2126590
DOI: 10.1093/oxfordjournals.molbev.a040622

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolutionary relationships of class II major-histocompatibility-complex genes in mammals.PMID 2126590Read ↗

Evolutionary relationship of HLA-DRB genes inferred from intron sequences.Semantic proximity Read ↗

Origins and divergence times of mammalian class II MHC gene clusters.Semantic proximity Read ↗

Evolution of HLA class-II polymorphism in primates: the DQA locus.Semantic proximity Read ↗

Locus specificity of polymorphic alleles and evolution by a birth-and-death process in mammalian MHC genes.Semantic proximity Read ↗

Giant panda genomic data provide insight into the birth-and-death process of mammalian major histocompatibility complex class II genes.Semantic proximity Read ↗

Evolution of class I major histocompatibility complex genes and molecules in humans and apes.Semantic proximity Read ↗

Evolution of the human HLA-DR regionSemantic proximity Read ↗

Evolutionary relationships among the primate Mhc-DQA1 and DQA2 alleles.Semantic proximity Read ↗

The orthologs of HLA-DQ and -DP genes display abundant levels of variability in macaque species.Semantic proximity Read ↗

Evolution of major histocompatibility complex class I genes in Cetartiodactyls.Semantic proximity Read ↗

Primate MHC class I from GenomesSemantic proximity Read ↗

The evolution of major histocompatibility class I genes in primates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.