Molecular, cellular, and physiological significance of N-terminal acetylation.

Abstract excerpt

Protein N-terminal acetylation is catalyzed by N-terminal acetyltransferases and represents one of the most common protein modifications in eukaryotes. An increasing number of studies report on the importance of N-terminal acetylation for protein degradation, complex formation, subcellular targeting, and protein folding. N-terminal acetyltransferases are recognized to play important roles in a diversity of...

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