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Article

Differential histone H3 Lys-9 and Lys-27 methylation profiles on the X chromosome.

Molecular and cellular biology - 1 Jun 2004

Rougeulle Claire, Chaumeil Julie, Sarma Kavitha, Allis C David, Reinberg Danny, Avner Philip, Heard Edith

Abstract excerpt

Histone H3 tail modifications are among the earliest chromatin changes in the X-chromosome inactivation process. In this study we investigated the relative profiles of two important repressive marks on the X chromosome: methylation of H3 lysine 9 (K9) and 27 (K27). We found that both H3K9 dimethylation and K27 trimethylation characterize the inactive X in somatic cells and that their relative kinetics of...

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Identifiers

PMID: 15169908
DOI: 10.1128/MCB.24.12.5475-5484.2004
PMCID: PMC419884

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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