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Article

PTMs on H3 variants before chromatin assembly potentiate their final epigenetic state.

Molecular cell - 20 Oct 2006

Loyola Alejandra, Bonaldi Tiziana, Roche Danièle, Imhof Axel, Almouzni Geneviève

Abstract excerpt

Histone posttranslational modifications (PTMs) and sequence variants regulate genome function. Although accumulating evidence links particular PTM patterns with specific genomic loci, our knowledge concerning where and when these PTMs are imposed remains limited. Here, we find that lysine methylation is absent prior to histone incorporation into chromatin, except at H3K9. Nonnucleosomal H3.1 and H3.3 show...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17052464
DOI: 10.1016/j.molcel.2006.08.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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