Article
Differential patterns of histone methylation and acetylation distinguish active and repressed alleles at X-linked genes.
Cytogenetic and genome research - 1 Jan 2002
Goto Y, Gomez M, Brockdorff N, Feil R
Abstract excerpt
In female mammals, one of the two X chromosomes is inactivated to compensate for the difference in dosage of X-linked genes between males and females. X inactivation involves sequential alterations to the chromatin that ultimately lead to the transcriptional repression of genes on the X chromosome. Here, histone methylation and acetylation along X-linked genes are investigated by chromatin immunoprecipitation...
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