Article
Use of embryonic stem cells to study mutations affecting postimplantation development in the mouse.
Ciba Foundation symposium - 1 Jan 1992
Robertson E J, Conlon F L, Barth K S, Costantini F, Lee J J
Abstract excerpt
The generation and analysis of insertional mutations that perturb early postimplantation development provide a means to identify genes required at this stage of embryogenesis. We have been studying two independently generated insertional mutations termed 413.d and H beta 58 that result in early p...
Topics
- Animals
- Cell Line
- Embryonic Development
- Embryonic and Fetal Development
- Female
- Genes, Lethal
- Genes, Recessive
- Mice
- Mutagenesis, Insertional
- Mutation
- Pregnancy
- Stem Cells