Article
H beta 58, an insertional mutation affecting early postimplantation development of the mouse embryo.
Development (Cambridge, England) - 1 Mar 1991
Radice G, Lee J J, Costantini F
Abstract excerpt
The generation and analysis of insertional mutations affecting mouse embryogenesis provides a powerful method to identify new genes that function in early development. In this paper, we describe an insertional mutation that interferes with postimplantation mouse development beginning at the time...
Topics
- Animals
- Blotting, Southern
- Chromosome Mapping
- Cloning, Molecular
- Embryo, Mammalian
- Gastrula
- Genes, Lethal
- Mice
- Mice, Transgenic
- Morphogenesis
- Mutagenesis, Insertional
- Phenotype
