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Article

Molecular genetics of maternally-controlled cell divisions.

PLoS genetics - 1 Apr 2020

Abrams Elliott W, Fuentes Ricardo, Marlow Florence L, Kobayashi Manami, Zhang Hong, Lu Sumei, Kapp Lee, Joseph Shai R, Kugath Amy, Gupta Tripti, Lemon Virginia, Runke Greg, Amodeo Amanda A, Vastenhouw Nadine L, Mullins Mary C

Abstract excerpt

Forward genetic screens remain at the forefront of biology as an unbiased approach for discovering and elucidating gene function at the organismal and molecular level. Past mutagenesis screens targeting maternal-effect genes identified a broad spectrum of phenotypes ranging from defects in oocyte development to embryonic patterning. However, earlier vertebrate screens did not reach saturation, anticipated classes...

Read the complete abstract on PubMed

Topics

Alleles
Animals
Blastula
Body Patterning
Cell Division
Cell Nucleus

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Cytokinesis

Embryonic Development

Female

Infertility, Male

Male

Maternal Inheritance

Mutagenesis

Mutation

Phenotype

Zebrafish

Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 32267837
DOI: 10.1371/journal.pgen.1008652
PMCID: PMC7179931

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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