Article
Characterization of critical interactions between Ndt80 and MSE DNA defining a novel family of Ig-fold transcription factors.
Nucleic acids research - 1 Jan 2004
Fingerman Ian M, Sutphen Kristina, Montano Sherwin P, Georgiadis Millie M, Vershon Andrew K
Abstract excerpt
The Ndt80 protein of the yeast Saccharomyces cerevisiae is the founding member of a new sub-family of proteins in the Ig-fold superfamily of transcription factors. The crystal structure of Ndt80 bound to DNA shows that it makes contacts through several loops on one side of the protein that connect beta-strands which form the beta-sandwich fold common to proteins in this superfamily. However, the DNA-binding...
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