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Article

Principles of protein-DNA recognition revealed in the structural analysis of Ndt80-MSE DNA complexes.

Structure (London, England : 1993) - 1 Mar 2006

Lamoureux Jason S, Glover J N Mark

Abstract excerpt

The Saccharomyces cerevisiae transcription factor Ndt80 selectively binds a DNA consensus sequence (the middle sporulation element [MSE]) to activate gene expression after the successful completion of meiotic recombination. Here we report the X-ray crystal structures of Ndt80 bound to ten distinct MSE variants. Comparison of these structures with the structure of Ndt80 bound to a consensus MSE reveals structural...

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Identifiers

PMID: 16531239
DOI: 10.1016/j.str.2005.11.017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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