Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The N-terminus of IntDOT forms hydrophobic interactions during Holliday Junction resolution.

Plasmid - 1 Jan 2000

Kolakowski Adam J, Gardner Jeffrey F

Abstract excerpt

DOT Integrase (IntDOT) is a member of the tyrosine recombinase family. It catalyzes the integration and excision reactions of an integrative and conjugative element (ICE) called CTnDOT. Like other tyrosine recombinases, the integration reaction proceeds by two sets of strand exchanges between the attDOT site on CTnDOT and an attB site in the host chromosome. The strand exchanges occur seven bases apart and define...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteroides
Share to Catalysis
Share to Conjugation, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydrophobic and Hydrophilic Interactions

Share to Integrases

Share to Mutation

Share to Protein Binding

Share to Protein Interaction Domains and Motifs

Source

Open in PubMed Open full text

Identifiers

PMID: 27422335
DOI: 10.1016/j.plasmid.2016.07.003
PMCID: PMC5121019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The N-terminus of IntDOT forms hydrophobic interactions during Holliday Junction resolution.PMID 27422335Read ↗

Mutational analysis and homology-based modeling of the IntDOT core-binding domain.Semantic proximity Read ↗

Structure of the Holliday junction intermediate in Cre-loxP site-specific recombination.Semantic proximity Read ↗

The Xis2d protein of CTnDOT binds to the intergenic region between the mob and tra operons.Semantic proximity Read ↗

CTnDOT integrase interactions with attachment site DNA and control of directionality of the recombination reaction.Semantic proximity Read ↗

Preliminary study on the DNA-binding properties of phage ΦC31 integrase.Semantic proximity Read ↗

DNA binding and synapsis by the large C-terminal domain of phiC31 integrase.Semantic proximity Read ↗

Regulation of site-specific recombination by the C-terminus of lambda integrase.Semantic proximity Read ↗

Attenuating functions of the C terminus of lambda integrase.Semantic proximity Read ↗

The efficiency of mispaired ligations by lambda integrase is extremely sensitive to context.Semantic proximity Read ↗

Holliday junction affinity of the base excision repair factor Endo III contributes to cholera toxin phage integration.Semantic proximity Read ↗

Structural basis for broad DNA-specificity in integron recombination.Semantic proximity Read ↗

Mutations at residues 282, 286, and 293 of phage lambda integrase exert pathway-specific effects on synapsis and catalysis in recombination.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.