Article
Sum1 and Ndt80 proteins compete for binding to middle sporulation element sequences that control meiotic gene expression.
Molecular and cellular biology - 1 Jul 2003
Pierce Michael, Benjamin Kirsten R, Montano Sherwin P, Georgiadis Millie M, Winter Edward, Vershon Andrew K
Abstract excerpt
A key transition in meiosis is the exit from prophase and entry into the nuclear divisions, which in the yeast Saccharomyces cerevisiae depends upon induction of the middle sporulation genes. Ndt80 is the primary transcriptional activator of the middle sporulation genes and binds to a DNA sequence element termed the middle sporulation element (MSE). Sum1 is a transcriptional repressor that binds to MSEs and...
Topics
- Amino Acid Sequence
- Binding, Competitive
- DNA-Binding Proteins
- Gene Expression Regulation, Fungal
- Meiosis
- Mitogen-Activated Protein Kinases
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Regulatory Sequences, Nucleic Acid
- Repressor Proteins
- Saccharomyces cerevisiae