Article
Expression of the DAL80 gene, whose product is homologous to the GATA factors and is a negative regulator of multiple nitrogen catabolic genes in Saccharomyces cerevisiae, is sensitive to nitrogen catabolite repression.
Molecular and cellular biology - 1 Dec 1991
Cunningham T S, Cooper T G
Abstract excerpt
We have cloned the negative regulatory gene (DAL80) of the allantoin catabolic pathway, characterized its structure, and determined the physiological conditions that control DAL80 expression and its influence on the expression of nitrogen catabolic genes. Disruption of the DAL80 gene demonstrated that it regulates multiple nitrogen catabolic pathways. Inducer-independent expression was observed for the allantoin...
Topics
- Allantoin
- Amino Acid Sequence
- Base Sequence
- Blotting, Northern
- Carbon-Nitrogen Ligases
- Cloning, Molecular
- DNA, Fungal
- Fungal Proteins
- GATA Transcription Factors
- Gene Expression Regulation, Fungal