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Article

GAL4 mutations that separate the transcriptional activation and GAL80-interactive functions of the yeast GAL4 protein.

Genetics - 1 May 1990

Salmeron J M, Leuther K K, Johnston S A

Abstract excerpt

The carboxy-terminal 28 amino acids of the Saccharomyces cerevisiae transcriptional activator protein GAL4 execute two functions--transcriptional activation and interaction with the negative regulatory protein, GAL80. Here we demonstrate that these two functions are separable by single amino acid changes within this region. We determined the sequences of four GAL4C-mutations, and characterized the abilities of...

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Identifiers

PMID: 2187743
DOI: 10.1093/genetics/125.1.21
PMCID: PMC1204005

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Source receipt: pubmed, retrieved 7 Sept 2026.

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