Article
Alternative processing events in human FMO genes.
Molecular pharmacology - 1 Jun 2004
Lattard Virginie, Zhang Jun, Cashman John R
Abstract excerpt
In humans, flavin-containing monooxygenase (FMO) functional diversity is determined by the expression of five FMO genes, named FMO1 to FMO5, and their variants. In this study, we systematically analyzed transcripts of FMO1 to FMO5 in different human tissues by reverse-transcription-polymerase chain reaction and identified a large number of splice variants. Exon skipping was the major splicing event observed....
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