Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification and functional analysis of common human flavin-containing monooxygenase 3 genetic variants.

The Journal of pharmacology and experimental therapeutics - 1 Jan 2007

Koukouritaki Sevasti B, Poch Mark T, Henderson Marilyn C, Siddens Lisbeth K, Krueger Sharon K, VanDyke Jonathan E, Williams David E, Pajewski Nicholas M, Wang Tao, Hines Ronald N

Abstract excerpt

Flavin-containing monooxygenases (FMOs) are important for the disposition of many therapeutics, environmental toxicants, and nutrients. FMO3, the major adult hepatic FMO enzyme, exhibits significant interindividual variation. Eighteen FMO3 single-nucleotide polymorphism (SNP) frequencies were determined in 202 Hispanics (Mexican descent), 201 African Americans, and 200 non-Latino whites. Using expressed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American
Share to Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hispanic or Latino

Share to Kinetics

Share to Oxygenases

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Share to White People

Source

Identifiers

PMID: 17050781
DOI: 10.1124/jpet.106.112268

Genes

FMO3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification and functional analysis of common human flavin-containing monooxygenase 3 genetic variants.PMID 17050781Read ↗

Discovery of novel flavin-containing monooxygenase 3 (FMO3) single nucleotide polymorphisms and functional analysis of upstream haplotype variants.Semantic proximity Read ↗

Population distribution of human flavin-containing monooxygenase form 3: gene polymorphisms.Semantic proximity Read ↗

Survey of variants of human flavin-containing monooxygenase 3 (FMO3) and their drug oxidation activities.Semantic proximity Read ↗

Two new polymorphisms of the FMO3 gene in Caucasian and African-American populations: comparative genetic and functional studies.Semantic proximity Read ↗

Human flavin-containing monooxygenase (form 3): polymorphisms and variations in chemical metabolism.Semantic proximity Read ↗

Haplotype and functional analysis of four flavin-containing monooxygenase isoform 2 (FMO2) polymorphisms in Hispanics.Semantic proximity Read ↗

Flavin-containing monooxygenase 3 (FMO3): genetic variants and their consequences for drug metabolism and diseaseSemantic proximity Read ↗

Flavin-containing monooxygenase 3 and human disease.Semantic proximity Read ↗

Flavin-containing monooxygenase genetic polymorphism: impact on chemical metabolism and drug development.Semantic proximity Read ↗

Genetic Polymorphisms of Human Flavin-Containing Monooxygenase 3: Implications for Drug Metabolism and Clinical PerspectivesSemantic proximity Read ↗

Allele and genotype frequencies of polymorphic FMO3 gene in two genetically distinct populations.Semantic proximity Read ↗

Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.