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Article

Flavin-containing monooxygenase genetic polymorphism: impact on chemical metabolism and drug development.

Pharmacogenomics - 1 Dec 2005

Koukouritaki Sevasti B, Hines Ronald N

Abstract excerpt

The flavin-containing monooxygenases (FMOs) metabolize a broad range of therapeutics. Consisting of five gene products in humans (FMO1-5), the different FMO family members exhibit pronounced tissue- and temporal-specific expression patterns. Substantial interindividual differences are also observed, and the inability to modulate with exogenous agents is consistent with an important role for genetic variation....

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Source

Identifiers

PMID: 16296944
DOI: 10.2217/14622416.6.8.807

Genes

FMO1
FMO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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