Article
Flavin-containing monooxygenase genetic polymorphism: impact on chemical metabolism and drug development.
Pharmacogenomics - 1 Dec 2005
Koukouritaki Sevasti B, Hines Ronald N
Abstract excerpt
The flavin-containing monooxygenases (FMOs) metabolize a broad range of therapeutics. Consisting of five gene products in humans (FMO1-5), the different FMO family members exhibit pronounced tissue- and temporal-specific expression patterns. Substantial interindividual differences are also observ...
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