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Article

The flavin-containing monooxygenase 2 gene (FMO2) of humans, but not of other primates, encodes a truncated, nonfunctional protein.

The Journal of biological chemistry - 13 Nov 1998

Dolphin C T, Beckett D J, Janmohamed A, Cullingford T E, Smith R L, Shephard E A, Phillips I R

Abstract excerpt

Flavin-containing monooxygenases (FMOs) are NADPH-dependent flavoenzymes that catalyze the oxidation of heteroatom centers in numerous drugs and xenobiotics. FMO2, or "pulmonary" FMO, one of five forms of the enzyme identified in mammals, is expressed predominantly in lung and differs from other...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Catalysis
Codon, Nonsense
Codon, Terminator
Humans
Macaca fascicularis
Molecular Sequence Data
Oxygenases
Pan troglodytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Messenger

Ribonucleases

Source

Identifiers

PMID: 9804831
DOI: 10.1074/jbc.273.46.30599

Genes

FMO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9804831-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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The flavin-containing monooxygenase 2 gene (FMO2) of humans, but not of other primates, encodes a truncated, nonfunctional protein.PMID 9804831Read ↗

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Identification and characterization of the FMO2 gene in Rattus norvegicus: a good model to study metabolic and toxicological consequences of the FMO2 polymorphism.Semantic proximity Read ↗

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Ethnic differences in human flavin-containing monooxygenase 2 (FMO2) polymorphisms: detection of expressed protein in African-Americans.Semantic proximity Read ↗

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