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Article

Survey of variants of human flavin-containing monooxygenase 3 (FMO3) and their drug oxidation activities.

Biochemical pharmacology - 1 Jun 2013

Yamazaki Hiroshi, Shimizu Makiko

Abstract excerpt

Human flavin-containing monooxygenase 3 (FMO3, EC 1.14.13.8) in liver catalyzes a variety of oxygenations of nitrogen- and sulfur-containing medicines and xenobiotic substances. Loss-of-function mutations of the FMO3 gene, the enzyme responsible for trimethylamine N-oxygenation, cause the inherited disorder trimethylaminuria (also known as fish odor syndrome). In this mini-review, mutations of the FMO3 gene...

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Source

Identifiers

PMID: 23567996
DOI: 10.1016/j.bcp.2013.03.020

Genes

FMO3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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