Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular analysis of telomere fusions in Arabidopsis: multiple pathways for chromosome end-joining.

The EMBO journal - 2 Jun 2004

Heacock Michelle, Spangler Elizabeth, Riha Karel, Puizina Jasna, Shippen Dorothy E

Abstract excerpt

End-to-end fusion of critically shortened telomeres in higher eucaryotes is presumed to be mediated by nonhomologous end-joining (NHEJ). Here we describe two PCR-based methods to monitor telomere length and examine the fate of dysfunctional telomeres in Arabidopsis lacking the catalytic subunit of telomerase (TERT) and the DNA repair proteins Ku70 and Mre11. Primer extension telomere repeat amplification relies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arabidopsis
Share to Arabidopsis Proteins
Share to Catalytic Domain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Plant

Share to DNA Repair

Share to MRE11 Homologue Protein

Share to Telomerase

Share to Telomere

Source

Open in PubMed Open full text

Identifiers

PMID: 15141167
DOI: 10.1038/sj.emboj.7600236
PMCID: PMC419913

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular analysis of telomere fusions in Arabidopsis: multiple pathways for chromosome end-joining.PMID 15141167Read ↗

Telomere dynamics and fusion of critically shortened telomeres in plants lacking DNA ligase IV.Semantic proximity Read ↗

Ku is required for telomeric C-rich strand maintenance but not for end-to-end chromosome fusions in Arabidopsis.Semantic proximity Read ↗

Telomere stability and development of ctc1 mutants are rescued by inhibition of EJ recombination pathways in a telomerase-dependent manner.Semantic proximity Read ↗

Ku suppresses formation of telomeric circles and alternative telomere lengthening in Arabidopsis.Semantic proximity Read ↗

Parameters Affecting Telomere-Mediated Chromosomal Truncation in ArabidopsisSemantic proximity Read ↗

Genome stability in Arabidopsis cells exhibiting alternative lengthening of telomeres.Semantic proximity Read ↗

A hypomorphic allele of telomerase uncovers the minimal functional length of telomeres in Arabidopsis.Semantic proximity Read ↗

Telomere rapid deletion regulates telomere length in Arabidopsis thaliana.Semantic proximity Read ↗

End joining at Caenorhabditis elegans telomeres.Semantic proximity Read ↗

Disruption of the Arabidopsis AtKu80 gene demonstrates an essential role for AtKu80 protein in efficient repair of DNA double-strand breaks in vivo.Semantic proximity Read ↗

Ku80 plays a role in non-homologous recombination but is not required for T-DNA integration in Arabidopsis.Semantic proximity Read ↗

RAD51 and RTEL1 compensate telomere loss in the absence of telomerase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.