Article
Ku is required for telomeric C-rich strand maintenance but not for end-to-end chromosome fusions in Arabidopsis.
Proceedings of the National Academy of Sciences of the United States of America - 21 Jan 2003
Riha Karel, Shippen Dorothy E
Abstract excerpt
Telomere dysfunction arising from mutations in telomerase or in telomere capping proteins leads to end-to-end chromosome fusions. Paradoxically, the Ku7080 heterodimer, essential for nonhomologous end-joining double-strand break repair, is also found at telomeres, and in mammals it is required to prevent telomere fusion. Previously, we showed that inactivation of Ku70 in Arabidopsis results in telomere...
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