Article
Genome stability in Arabidopsis cells exhibiting alternative lengthening of telomeres.
Cytogenetic and genome research - 1 Jan 2008
Akimcheva S, Zellinger B, Riha K
Abstract excerpt
Indefinite proliferation of eukaryotic cells depends on telomerase that counteracts the depletion of DNA from chromosome termini due to the end replication problem. The requirement for telomerase can, under certain conditions, be circumvented by employing homologous recombination-based mechanisms for telomere maintenance. Whereas yeast and mammalian cells lacking telomerase appear to readily adopt alternative...
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