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Article

RAD51 and RTEL1 compensate telomere loss in the absence of telomerase.

Nucleic acids research - 16 Mar 2018

Olivier Margaux, Charbonnel Cyril, Amiard Simon, White Charles I, Gallego Maria E

Abstract excerpt

Replicative erosion of telomeres is naturally compensated by telomerase and studies in yeast and vertebrates show that homologous recombination can compensate for the absence of telomerase. We show that RAD51 protein, which catalyzes the key strand-invasion step of homologous recombination, is localized at Arabidopsis telomeres in absence of telomerase. Blocking the strand-transfer activity of the RAD51 in...

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Share to Genomic Instability
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29346668
DOI: 10.1093/nar/gkx1322
PMCID: PMC5861403

Genes

RAD51
RTEL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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