Article
Telomere dynamics and fusion of critically shortened telomeres in plants lacking DNA ligase IV.
Nucleic acids research - 1 Jan 2007
Heacock Michelle L, Idol Rachel A, Friesner Joanna D, Britt Anne B, Shippen Dorothy E
Abstract excerpt
In the absence of the telomerase, telomeres undergo progressive shortening and are ultimately recruited into end-to-end chromosome fusions via the non-homologous end joining (NHEJ) double-strand break repair pathway. Previously, we showed that fusion of critically shortened telomeres in Arabidopsis proceeds with approximately the same efficiency in the presence or absence of KU70, a key component of NHEJ. Here we...
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