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Article

Ku80 plays a role in non-homologous recombination but is not required for T-DNA integration in Arabidopsis.

The Plant journal : for cell and molecular biology - 1 Sept 2003

Gallego M E, Bleuyard J-Y, Daoudal-Cotterell S, Jallut N, White C I

Abstract excerpt

Chromosomal breaks are repaired by homologous recombination (HR) or non-homologous end joining (NHEJ) mechanisms. The Ku70/Ku80 heterodimer binds DNA ends and plays roles in NHEJ and telomere maintenance in organisms ranging from yeast to humans. We have previously identified a ku80 mutant of the model plant Arabidopsis thaliana and shown the role of Ku80 in telomere homeostasis in plant cells. We show here that...

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Identifiers

PMID: 12940949
DOI: 10.1046/j.1365-313x.2003.01827.x

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Ku80 plays a role in non-homologous recombination but is not required for T-DNA integration in Arabidopsis.PMID 12940949Read ↗

Telomere length deregulation and enhanced sensitivity to genotoxic stress in Arabidopsis mutants deficient in Ku70.Semantic proximity Read ↗

Disruption of the Arabidopsis AtKu80 gene demonstrates an essential role for AtKu80 protein in efficient repair of DNA double-strand breaks in vivo.Semantic proximity Read ↗

Involvement of KU80 in T-DNA integration in plant cells.Semantic proximity Read ↗

Ku suppresses formation of telomeric circles and alternative telomere lengthening in Arabidopsis.Semantic proximity Read ↗

The INO80 protein controls homologous recombination in Arabidopsis thaliana.Semantic proximity Read ↗

Telomerase dependence of telomere lengthening in Ku80 mutant Arabidopsis.Semantic proximity Read ↗

Ku is required for telomeric C-rich strand maintenance but not for end-to-end chromosome fusions in Arabidopsis.Semantic proximity Read ↗

Increased telomere length and hypersensitivity to DNA damaging agents in an Arabidopsis KU70 mutant.Semantic proximity Read ↗

Telomere dynamics and fusion of critically shortened telomeres in plants lacking DNA ligase IV.Semantic proximity Read ↗

Molecular analysis of telomere fusions in Arabidopsis: multiple pathways for chromosome end-joining.Semantic proximity Read ↗

The telomere-binding protein KU is required for DSB repair in rice mitosis but not in meiosis.Semantic proximity Read ↗

Ku80- and DNA ligase IV-deficient plants are sensitive to ionizing radiation and defective in T-DNA integration.Semantic proximity Read ↗

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