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Genome-wide linkage analysis of chromogranin B expression in the CEPH pedigrees: implications for exocytotic sympathochromaffin secretion in humans.

Physiological genomics - 17 Jun 2004

Greenwood Tiffany A, Cadman Peter E, Stridsberg Mats, Nguyen Susan, Taupenot Laurent, Schork Nicholas J, O'Connor Daniel T

Abstract excerpt

Chromogranin B (CgB), a major member of the chromogranin/secretogranin family of catecholamine storage vesicle secretory proteins, plays both intracellular (vesiculogenic) and extracellular (prohormone) roles in the neuroendocrine system, and its biosynthesis and release are under the control of efferent sympathetic nerve traffic ("stimulus-transcription coupling"). To explore the role of heredity in control of...

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PMID: 15138309
DOI: 10.1152/physiolgenomics.00104.2003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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