Diurnal effect on caffeine acetylation phenotyping: a preliminary report.

doi:10.1515/dmdi.1992.10.1-2.163

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Article

Diurnal effect on caffeine acetylation phenotyping: a preliminary report.

Drug metabolism and drug interactions - 1 Jan 1992

Hashiguchi M, Fujimura A, Ohashi K, Ebihara A

Abstract excerpt

The present study examined whether caffeine acetylation phenotype could be altered by its time of administration. Caffeine was given orally to nine healthy subjects at 10 a.m. and 10 p.m. and acetylation phenotype was determined by measuring the major metabolites of caffeine in urine. The results...

Topics

Acetylation
Adult
Caffeine
Circadian Rhythm
Female
Humans
Male
Phenotype

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