Acetylation polymorphism of caffeine in a Japanese population.

doi:10.1038/clpt.1992.141

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Article

Acetylation polymorphism of caffeine in a Japanese population.

Clinical pharmacology and therapeutics - 1 Sept 1992

Hashiguchi M, Ebihara A

Abstract excerpt

The frequency distribution of N-acetylation of caffeine was determined in 140 unrelated healthy Japanese subjects by measuring the amount of two main metabolites of caffeine, 5-acetylamino-6-formyl-amino-3-methyluracil (AFMU) and 1-methylxanthine (1X), in urine after an oral dose of caffeine. N-A...

Topics

Acetylation
Adult
Caffeine
Humans
Japan
Male
Metabolism
Phenotype
Polymorphism, Genetic
Uracil
Xanthines

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