Article
Aromatic and heterocyclic amine metabolism and phenotyping in humans.
Progress in clinical and biological research - 1 Jan 1991
Lang N P, Kadlubar F F
Abstract excerpt
Our method to evaluate acetylator phenotype and N-oxidation phenotype with a single caffeine dose and a single urine specimen collection has enabled us to examine acetylation and N-oxidation by two enzyme systems that have a known genetic polymorphism and are important in aromatic amine metabolism. Based on available data, we have hypothesized patients with urinary bladder cancer will have a higher frequency of...
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