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Article

Aromatic and heterocyclic amine metabolism and phenotyping in humans.

Progress in clinical and biological research - 1 Jan 1991

Lang N P, Kadlubar F F

Abstract excerpt

Our method to evaluate acetylator phenotype and N-oxidation phenotype with a single caffeine dose and a single urine specimen collection has enabled us to examine acetylation and N-oxidation by two enzyme systems that have a known genetic polymorphism and are important in aromatic amine metabolism. Based on available data, we have hypothesized patients with urinary bladder cancer will have a higher frequency of...

Topics

Acetyltransferases
Amines
Carcinogens
Cytochrome P-450 CYP1A2
Cytochrome P-450 Enzyme System
Humans
Hydrocarbons
Neoplasms
Oxidoreductases
Phenotype
Risk Factors

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PMID: 1956928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1956928-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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