Article
Segregation analyses of four urinary caffeine metabolite ratios implicated in the determination of human acetylation phenotypes.
Genetic epidemiology - 1 Jan 1994
Vincent-Viry M, Pontes Z B, Gueguen R, Galteau M M, Siest G
Abstract excerpt
Human acetylation phenotypes were determined with caffeine (137X) as the test substance, improved by measuring urinary caffeine metabolites with a previously described HPLC method. Caffeine, 5-acetylamino-6-formylamino-3-methyluracil (AFMU), 1-methylxanthine (IX), 1-methyluric acid (IU), 1,7-dimethylxanthine (17X), and 1,7-dimethyluric acid (17U) were quantified. This study tested the hypothesis, suggested by...
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