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Article

NAT2 and CYP1A2 phenotyping with caffeine: head-to-head comparison of AFMU vs. AAMU in the urine metabolite ratios.

British journal of clinical pharmacology - 1 Jan 2003

Nyéki A, Buclin T, Biollaz J, Decosterd L A

Abstract excerpt

AIMS: (i) To compare the phenotyping of healthy subjects for NAT2 and CYP1A2 activities with caffeine, by the simultaneous assay of the urinary metabolites AFMU and AAMU, and (ii) to ascertain whether NAT2 and CYP1A2 phenotyping is influenced by the use of AFMU or AAMU in the metabolite ratio. METHODS: Thirty-five healthy subjects (16 men, 19 women) participated to the study. Caffeine metabolite concentrations...

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Identifiers

PMID: 12534641
DOI: 10.1046/j.1365-2125.2003.01730.x
PMCID: PMC1884184

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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