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Article

Aurora kinases link chromosome segregation and cell division to cancer susceptibility.

Current opinion in genetics & development - 1 Feb 2004

Meraldi Patrick, Honda Reiko, Nigg Erich A

Abstract excerpt

Aurora kinases play critical roles in chromosome segregation and cell division. They are implicated in the centrosome cycle, spindle assembly, chromosome condensation, microtubule-kinetochore attachment, the spindle checkpoint and cytokinesis. Aurora kinases are regulated through phosphorylation, the binding of specific partners and ubiquitin-dependent proteolysis. Several Aurora substrates have been identified...

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Source

Identifiers

PMID: 15108802
DOI: 10.1016/j.gde.2003.11.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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