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Article

Aurora-A: the maker and breaker of spindle poles.

Journal of cell science - 1 Sept 2007

Barr Alexis R, Gergely Fanni

Abstract excerpt

The gene encoding the Aurora-A protein kinase is located in the 20q13 breast cancer amplicon and is also overexpressed in colorectal, pancreatic and gastric tumours. Although Aurora-A may not be a bona fide oncoprotein in humans, it is a promising drug target in cancer therapy. Thus, it is surprising that so little is known of its role in normal cells. The primary function of Aurora-A is to promote bipolar...

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Identifiers

PMID: 17715155
DOI: 10.1242/jcs.013136

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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