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Article

Signature of the oligomeric behaviour of nuclear receptors at the sequence and structural level.

EMBO reports - 1 Apr 2004

Brelivet Yann, Kammerer Sabrina, Rochel Natacha, Poch Olivier, Moras Dino

Abstract excerpt

Nuclear receptors (NRs) are ligand-dependent transcription factors that control a large number of physiological events through the regulation of gene transcription. NRs function either as homodimers or as heterodimers with retinoid X receptor/ultraspiracle protein (RXR/USP). A structure-based sequence analysis aimed at discovering the molecular mechanism that controls the dimeric association of the ligand-binding...

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Identifiers

PMID: 15105832
DOI: 10.1038/sj.embor.7400119
PMCID: PMC1299030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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