Article
Evolution of the repertoire of nuclear receptor binding sites in genomes.
Molecular and cellular endocrinology - 1 Mar 2011
Cotnoir-White David, Laperrière David, Mader Sylvie
Abstract excerpt
Nuclear receptors (NRs) are ligand-dependent transcription factors with important roles in normal development and physiology and in a wide array of pathologies. While identification of natural or synthetic ligands for all human NRs has clarified their physiological roles and led to numerous therapeutic applications, much remains to be understood about the mechanisms by which NRs control transcription of specific...
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