Article
Evolution of the nuclear receptor superfamily: early diversification from an ancestral orphan receptor.
Journal of molecular endocrinology - 1 Dec 1997
Laudet V
Abstract excerpt
From a database containing the published nuclear hormone receptor (NR) sequences I constructed an alignment of the C, D and E domains of these molecules. Using this alignment, I have performed tree reconstruction using both distance matrix and parsimony analysis. The robustness of each branch was...
Topics
- Animals
- Databases as Topic
- Evolution, Molecular
- Genetic Variation
- Humans
- Multigene Family
- Mutation
- Phylogeny
- Protein Structure, Tertiary
- Receptors, Cytoplasmic and Nuclear