Maturing of the nuclear receptor family.

doi:10.1172/JCI92949

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Article

Maturing of the nuclear receptor family.

The Journal of clinical investigation - 3 Apr 2017

Lazar Mitchell A

Abstract excerpt

Members of the nuclear receptor (NR) superfamily of ligand-regulated transcription factors play important roles in reproduction, development, and physiology. In humans, genetic mutations in NRs are causes of rare diseases, while hormones and drugs that target NRs are in widespread therapeutic use. The present issue of the JCI includes a series of Review articles focused on specific NRs and their wide range of...

Topics

Animals
Genetic Diseases, Inborn
Humans
Mutation
Receptors, Cytoplasmic and Nuclear

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Identifiers

PMID: 28368290
DOI: 10.1172/JCI92949
PMCID: PMC5373857

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